PhD project at the University of Zurich

PhD Project Title: C-H functionalization reactions with alkenes as directing groups

Principal Investigator: Prof. Dr. Cristina Nevado

PhD Project description: the objectives of this project is the direct conversion of olefin containing feedstock into high value-added building blocks.

In this project we aim to:

1) develop earth-abundant metal catalyzed protocols for the functionalization of olefins

2) design ligand templates that enable the migration of the C(sp3)-M bond across the aliphatic systems in a stereocontrolled manner

3) Investigate the functionalization of in situ produced remote organo-radical/metal intermediates towards C-C and C-X (X = O, N, Halogen) bond forming reactions

4) The newly developed reactions will be used to prepare building blocks of value for the industrial partners.

Relevant skills that will be considered are:

  • Strong theoretical background and practical skills in organic synthesis and catalysis
  • Practical experience in analytical methods (NMR, MS, HPLC)
  • Good level of English proficiency (understood, spoken and written)
  • Skills in scientific writing (reports, papers, etc.)
  • Team spirit and collaborative predisposition

Planned secondments:

ESR4 will be seconded to Syngenta (M18-M20) and Astrazeneca (M30-M32).