The Project

C1-4 Alkylation of Aryl Bromides with Light Alkanes enabled by Metallaphotocatalysis in Flow

Authors: Antonio Pulcinella, Prakash Chandra Tiwari, Alberto Luridiana, Ken Yamazaki, Daniele Mazzarella, Akshay K. Sadhoe, Antonella Ilenia Alfano, Eveline H. Tiekink, Trevor A. Hamlin, Timothy Noel

in: Angew. Chem. Int. Ed.

Pd-Catalyzed C(sp2)–H/C(sp2)–H Coupling of Limonene

Authors: Marco Di Matteo, Anna Gagliardi, Alexandre Pradal, Luis F. Veiros, Fabrice Gallou, Giovanni Poli

in: Journal of Organic Chemistry, 2024

Fluorescent coumarin-alkynes for labeling of amino acids and peptides via manganese(I)-catalyzed C–H alkenylation

Authors: Adelina Kopp, Tsuyoshi Oyama and Lutz Ackermann

in: Chem Commun

Electrocatalytic Formal C(sp2)–H Alkylations via Nickel-Catalyzed Cross-Electrophile Coupling with Versatile Arylsulfonium Salts

Authors: Takuya Michiyuki, Simon L. Homölle, Neeraj Kumar Pandit, Lutz Ackermann

in: Angewandte Chemie Int. Ed.

Photo-Induced Ruthenium-Catalyzed C−H Arylation Polymerization at Ambient Temperature

Authors: Takuya Michiyuki, Isaac Maksso, Lutz Ackermann

in: Angewandte Chemie Int. Ed.

Easy access to polyhalogenated biaryls: regioselective (di)halogenation of hypervalent bromines and chlorines

Authors: Daniel Carter Martos, Maxime de Abreu, Pascal Hauk, Philipp Fackler and Joanna Wencel-Delord
in: Chemical Science

Tetraethylammonium Salts as Solid, Easy to Handle Ethylene Precursors and Their Application in Mizoroki–Heck Coupling

Authors: Eleni Papaplioura, Maëva Mercier, Michael E. Muratore, Tobias Biberger, Soufyan Jerhaoui, and Michael Schnürch
in: The Journal of Organic Chemistry

Photocatalytic Functionalization of Dehydroalanine-Derived Peptides in Batch and Flow

Authors: Nikolaos Kaplaneris, Merve Akdeniz, Méritxell Fillols, Francesca Arrighi, Fabian Raymenants, Gana Sanil, Daniel T. Gryko, Timothy Noel
in: Angew. Chem. Int. Ed. 2024, e202403271

Air-stable bis-cyclometallated iridium catalysts for ortho-directed C(sp2)–H borylation

Authors: Janis Zakis, Antonis Messinis, Lutz Ackermann, Tomas Smejkal, Joanna Wencel-Delord
in: Adv. Synth. Catal. 2024, in press.

Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water

Authors: Julia Struwe, Tsuyoshi Oyama, Fabrice Gallou, Lutz Ackermann
in: Synlett 2024, 35, A-E

Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes

Authors: Stefano Bonciolini, Antonio Pulcinella, Matteo Leone, Debora Schiroli, Adrián Luguera Ruiz, Andrea Sorato, Maryne A. J. Dubois, Ranganath Gopalakrishnan, Geraldine Masson, Nicola Della Ca’, Stefano Protti, Maurizio Fagnoni, Eli Zysman-Colman, Magnus Johansson & Timothy Noël
in: Nat Commun 15, 1509 (2024)

– 2023

Gold-Catalyzed 1,2-Aryl Shift and Double Alkyne Benzannulation

Authors: Gana Sanil, Maciej Krzeszewski, Wojciech Chaładaj,
Witold Danikiewicz, Iryna Knysh, Łukasz Dobrzycki, Olga Staszewska-Krajewska, Michał Cyrański, Denis Jacquemin, and Daniel T Gryko

in: Angew. Chem. Int. Ed.2023,e202311123

Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position

Authors: Pascal Hauk, Valérie Mazan, Fabrice Gallou, Joanna Wencel-Delord

in: Chem. Sci., 2023,14, 12049-12055

2-(o-Tolyl) Pyridine as Ligand Improves the Efficiency in Ketone Directed ortho-Arylation

Authors: Nanditha Kattukudiyil Narayanan, Ernst Pittenauer, Michael Schnürch
in: Eur. J. Chem., 2023, e202300759

Ruthenium-Catalyzed Aminocarbonylation with Isocyanates Through Weak Coordinating Groups

Authors: Elisa Y. Lai, Binbin Yuan, Lutz Ackermann, Magnus J. Johansson
in: Chem. Eur. J., 2023, e202302023

Late-stage peptide labeling with near-infrared fluorogenic nitrobenzodiazoles by manganese- catalyzed C–H activation

Authors: Tsuyoshi Oyama, Lorena Mendive-Tapia, Verity Cowell, Adelina Kopp, Marc Vendrell and Lutz Ackermann
in: Chem. Sci., 2023,14, 5728-5733

Photocatalytic Alkylation of C(sp3)−H Bonds Using Sulfonylhydrazones

Authors: Antonio Pulcinella, Stefano Bonciolini, Florian Lukas, Andrea Sorato, Timothy Noël
in: Angew. Chem. Int. Ed. 2023, 62, e202215374

– 2022

Remote C–H Glycosylation by Ruthenium(II) Catalysis: Modular Assembly of meta-C-Aryl Glycosides

Authors: Jun Wu, Nikolaos Kaplaneris, Julia Pöhlmann, Takuya Michiyuki, Binbin Yuan, Lutz Ackermann
in: Angew Chem. Int. Ed., 2022, e202208620

Modular allylation of C(sp3)−H bonds by combining decatungstate photocatalysis and HWE olefination in flow

Authors: Luca Capaldo, Stefano Bonciolini, Antonio Pulcinella, Manuel Nuno, Timothy Noel
in: Chemical Science, vol. 13, pp. 7325-7331, 2022

– 2021

Rapid and Direct Photocatalytic C(sp3)−H Acylation and Arylation in Flow

Authors: Daniele Mazzarella, Antonio Pulcinella, Loic Bovy, Remy Broersma, Timothy Noel
in: Angewandte Chemie International Edition, vol. 60, pp. 1-7, 2021

– 20224

Do we really need ligands in Ir-catalyzed C–H borylation?

Authors: Janis M. Zakis, Simone L. Kuhn, Joanna Wencel-Delord, Tomas Smejkal
in: Chimia 2024, 78, 513

The Vinyl Group: Small but Mighty – Transition Metal Catalyzed and Non-Catalyzed Vinylation Reactions

Authors: Eleni Papaplioura, Maëva Mercier, Soufyan Jerhaoui, Michael Schnürch
in: ChemCatChem 2024, e202400513

– 2022

Cyclometallated complexes as catalysts for C–H activation and functionalization

Authors: Janis Mikelis Zakis, Tomas Smejkal, Joanna Wencel-Delord
in: Chemical Communications, vol. 58, pp. 483-490, 2022

– 2021

Homogeneous catalytic C(sp3)–H functionalization of gaseous alkanes

Authors: Antonio Pulcinella, Daniele Mazzarella, Timothy Noel
in: Chemical Communications, vol. 57, pp. 9956-9967, 2021

Organic synthesis in Aqueous Multiphase Systems — Challenges and opportunities ahead of us

Authors: Pascal Hauk, Joanna Wencel-Delord, Lutz Ackermann, Peter Walde, Fabrice Gallou
in: Current Opinion in Colloid & Interface Science, vol. 101506, 2021